Unlike most supplements , these lab-made remedies—which claim that a capsule or liquid shot, taken just before you go to bed, will stop you from feeling like crap—just may help. However, some of the stuff is more legit than others. Let’s start by dissecting the dreaded hangover itself . First, alcohol makes you dehydrated. Next, your liver can’t keep up with the toxins you pounded. And lastly, booze messes with the chemicals in your brain that regulate the sleep-wake cycle . Overnight Expert: How To Conceal a Hangover Some products, like Thrive+ and Morning Recovery, claim to address all three. They contain electrolytes , which, along with water, may help to rehydrate and ease the headache. As for detoxification, milk thistle is a supposed remedy for liver disease. There’s not much evidence, but supplements containing vitamins B1 and B6 may help, says Myles Spar, M.D., an integrative physician and NBA adviser. Where science springs ahead is around brain recovery. The sleep-wa